Abstract This article discusses issues of rural space and rurality using as a research hypothesis the concept of integrated territorial redevelopment. We started the research with the question of overcoming the urban-rural dichotomy, presenting the formulations proposed by the culturalist, anti-urbanist and naturalist tradition of the 19th and 20th centuries, up to the new city-countryside partnership that is delineated, more recently, by international territorial strategies. The concept of integrated territorial redevelopment focuses on the notion of self-sustaining development and the relationship between territorial vocation and territorial tendency. The Village is assumed as a spatial social planning unit, both in its legal-instrumental dimension and in its rural habitat configuration. In the case study, in a region with low population density, the proposal for the activation of rural villages and the revitalization of the agro-sylvo-pastoral systems of the surrounding areas was elaborated on the basis of territorialization models based on endogenous factors in terms of their sustainability.

Résumé Cet article aborde les thèmes de l’espace rural et de la ruralité, en prenant comme hypothèse de recherche, le concept de réaménagement territorial intégré. Nous avons commencé la recherche par la question de surmonter la dichotomie ville-campagne, en présentant les formulations proposées par la tradition culturaliste, anti-urbaniste et naturaliste, des 19ème et 20ème siècles, jusqu’au nouveau partenariat ville-campagne délimité, plus récemment, par les stratégies territoriales internationales. Le concept de réaménagement territorial intégré se concentre sur la notion de développement autonome et sur la relation entre la vocation territoriale et la tendance territoriale. Le Village est conçue comme unité socio-spatial de planification, tant dans sa dimension juridico-instrumentale que dans sa configuration d’habitat rural. Dans l’étude de cas, dans une région à faible densité de population, la proposition d’activation des agglomérats ruraux et de revitalisation des systèmes agroforestiers-pastoraux des zones environnantes elle a été élaborée sur la base de modèles de territorialisation formulés sur des facteurs endogènes en vue de leur sou durabilité.

Resumen Este artículo discute las temáticas del espacio rural y de la ruralidad, tomando como hipótesis de investigación el concepto de redesarrollo territorial integrado. Comenzamos la investigación con la cuestión de superar la dicotomía ciudad-campo, presentando las formulaciones propuestas por la tradición culturalista, antiurbanista y naturalista de los siglos XIX y XX, a la nueva asociación ciudad-campo que ha sido delineada, recientemente, por las estrategias territoriales internacionales. El concepto de redesarrollo territorial integrado se centra en la noción de desarrollo autosostenible y en las relaciones entre vocación territorial y tendencia territorial. El Pueblo se adopta como una unidad socio-espacial de planificación, tanto en su dimensión jurídico-instrumental como en su configuración de hábitat rural. En el estudio de caso, en una región de baja densidad poblacional, se presentará la propuesta para la activación de aglomerados rurales y revitalización de sistemas agro-silvo-pastoriles de las áreas circundantes, elaborada con base en modelos de territorialización, formulados sobre factores endógenos en vista de su sostenibilidad.

Resumo Este artigo aborda as temáticas do espaço rural e da ruralidade, tomando como hipótese de pesquisa o conceito de redesenvolvimento territorial integrado. Iniciamos a pesquisa com a questão da superação da dicotomia cidade-campo, apresentando as formulações propostas pelas tradições culturalista, anti-urbanista e naturalista, dos séculos XIX e XX, até à nova parceria cidade-campo que vem a ser delineada, mais recentemente, pelas estratégias territoriais internacionais. O conceito de redesenvolvimento territorial integrado centra-se na noção de desenvolvimento auto-sustentado e nas relações entre vocação territorial e tendência territorial. A Aldeia é adotada como unidade espaço-social de planeamento, tanto na sua dimensão jurídico-instrumental como na sua configuração de habitat rural. No estudo de caso, em regiões de baixa densidade populacional, a proposta da ativação dos aglomerados rurais e revitalização dos sistemas agro-silvo-pastoris das áreas envolventes foi elaborada com base em modelos de territorialização, formulados sobre fatores endógenos tendo em vista a sua sustentabilidade.

Abstract Fecal Immunochemical Test (FIT) followed by a colonoscopy is an efficacious strategy to improve the adenoma detection rate and Colorectal Cancer (CRC). There is no organized national screening program for CRC in Brazil. The aim of this research was to describe the implementation of an organized screening program for CRC through FIT followed by colonoscopy, in an urban low-income community of São Paulo city. The endpoints of the study were: FIT participation rate, FIT positivity rate, colonoscopy compliance rate, Positive Predictive Values (PPV) for adenoma and CRC, and the rate of complications. From May 2016 to October 2019, asymptomatic individuals, 50-75 years old, received a free kit to perform the FIT. Positive FIT (≥ 50 ng/mL) individuals were referred to colonoscopy. 10,057 individuals returned the stool sample for analysis, of which (98.2%) 9,881 were valid. Women represented 64.8% of the participants. 55.3% of individuals did not complete elementary school. Positive FIT was 7.8% (776/9881). The colonoscopy compliance rate was 68.9% (535/776). There were no major colonoscopy complications. Adenoma were detected in 63.2% (332/525) of individuals. Advanced adenomatous lesions were found in 31.4% (165/525). CRC was diagnosed in 5.9% (31/525), characterized as adenocarcinoma: in situ in 3.2% (1/31), intramucosal in 29% (9/31), and invasive in 67.7% (21/31). Endoscopic treatment with curative intent for CRC was performed in 45.2% (14/31) of the cases. Therefore, in an urban low-income community, an organized CRC screening using FIT followed by colonoscopy ensued a high participation rate, and high predictive positive value for both, adenoma and CRC.

Abstract The objective of the present study is to evaluate the fluid dynamics of a flotation column (2" in diameter and 6 m in height) based on gas hold-up measurements and, in particular, by applying the liquid-phase RTD (residence time distribution) technique. Additionally, a comparative study is performed between different methodologies used to determine RTD hydrodynamic parameters such as fitting of tanks-in-series and axial dispersion models to the experimental data. The evidence indicates that the axial dispersion and tanks-in-series models agreed well with the experimental data, with a slight advantage of the first model, in terms of obtaining the fluid dynamic parameters. It was proven that the axial dispersion model parameters (Pe or Nd) can be obtained with good precision (R2 > 0.99) within the evaluated ranges from correlations that use the number of tanks in series (N) values estimated by the tanks-in-series model.

Resumo: Este artigo destaca uma rede de aquicultores na região centro-este da Amazônia brasileira, com base em discussões do grupo WhatsApp “Peixe de Rondônia”, entre agosto de 2016 e outubro de 2017, acerca de soluções para superar os desafios ambientais, sociais e econômicos. Para tanto, buscou-se verificar a utilidade dessa rede para o compartilhamento de informações com vista à promoção da sustentabilidade do setor, mediante técnicas de análise de rede social e análise de conteúdo na perspectiva exploratória, com apoio computacional dos softwares Gephi e Iramuteq, cujos resultados apontam que a rede total apresenta quatro classes com níveis de interação distintos e complementares e baixa densidade (0,038). A análise de conteúdo demonstrou a existência de cinco clusters de interesse: “mercado”, “grupo social”, “processos produtivos”, “legislação” e “normatização”. O cluster “mercado” apresenta robustez quanto à proximidade e à coesão, configurando-se em uma comunidade de prática ativa dos produtores terminadores. Preocupações com sustentabilidades econômica e ecológica foram constatadas, porém verificou-se que a rede não se constitui efetivamente em comunidade de prática, pois não há evidências de que as discussões promovidas no grupo, até o momento, geraram ações reais de contribuição para a sustentabilidade da atividade. As evidências indicam que os atores do grupo, individualmente, possuem interesse na concretização das ações propostas, no entanto constatou-se que ainda são necessárias tomada de conciência e organização coletiva para alcançar objetivos comuns com foco na sustentabilidade do setor.

Abstract: This article highlights a network of aquaculture farmers in the central-eastern region of the Brazilian Amazon based on the discussions of the WhatsApp group “Peixe de Rondônia”, between August/2016 and October/2017, about solutions to overcome environmental, social, and economic challenges. To this end, we sought to verify the usefulness of this network for sharing information to promote the sustainability of the sector. Using social network analysis techniques and content analysis in an exploratory perspective, with computational support from Gephi and Iramuteq software, the results show that the total network has four classes with different and complementary levels of interaction and low density (0.038). The content analysis demonstrated the existence of five clusters of interest: “market”, “social group”, “production processes”, “legislation” and “standardization”. The “market” cluster is robust in terms of proximity and cohesion, forming a community of active practice for terminating producers. The other classes are related to social components of the network and focus on institutional aspects: topics such as commercial, productive processes, and legal security are discussed. Concerns about economic and ecological sustainability were noted, but it was found that the network is not effectively constituted as a community of practice, as there is no evidence that the discussions promoted in the group, so far, have generated real actions to contribute to the sustainability of the activity. The evidence indicates that the group actors, individually, have an interest in the implementation of the proposed actions, however, it was found that there is still a need for awareness and collective organization to achieve common goals focused on the sustainability of the sector.

OBJECTIVES: Since the outbreak of the novel coronavirus disease 2019 (COVID-19), all health services worldwide underwent profound changes, leading to the suspension of many elective surgeries. This study aimed to evaluate the safety of elective colorectal surgery during the pandemic. METHODS: This was a retrospective, cross-sectional, single-center study. Patients who underwent elective colorectal surgery during the COVID-19 pandemic between March 10 and September 9, 2020, were included. Patient data on sex, age, diagnosis, types of procedures, hospital stay, mortality, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preoperative screening tests were recorded. RESULTS: A total of 103 colorectal surgical procedures were planned, and 99 were performed. Four surgeries were postponed due to positive preoperative screening for SARS-CoV-2. Surgical procedures were performed for colorectal cancer (n=90) and inflammatory bowel disease (n=9). Laparoscopy was the approach of choice for 43 patients (43.4%), 53 (53.5%) procedures were open, and 3 (3%) procedures were robotic. Five patients developed COVID-19 in the postoperative period, and three of them died in the intensive care unit (n=3/5, 60% mortality). Two other patients died due to surgical complications unrelated to COVID-19 (n=2/94, 2.1% mortality) (p<0.01). Hospital stay was longer in patients with SARS-CoV-2 infection than in those without (38.4 versushttps://doi.org/10.3 days, respectively, p<0.01). Of the 99 patients who received surgical care during the pandemic, 94 were safely discharged (95%). CONCLUSION: Our study demonstrated that elective colorectal surgical procedures may be safely performed during the pandemic; however, preoperative testing should be performed to reduce in-hospital infection rates, since the mortality rate due to SARS-CoV-2 in this setting is particularly high.

RESUMO Racional: Devido à falta de padrões normais de manometria anorretal no Brasil, os dados utilizados estão sujeitos a padrões de normalidade descritos em diferentes nacionalidades . Objetivo: Determinar os valores e a faixa da manometria anorretal de pessoas em idade produtiva, sem distúrbios do assoalho pélvico, comparando os parâmetros obtidos entre homens e mulheres. Métodos: Análise prospectiva de dados clínicos, como gênero, idade, raça, índice de massa corporal (IMC) e manometria anorretal, de voluntários de uma referência universitária brasileira em distúrbios do assoalho pélvico. Resultados: Quarenta pessoas foram incluídas, com idade média de 45,5 anos nos homens e 37,2 nas mulheres (p=0,43). De acordo com homens e mulheres, respectivamente em mmHg, as pressões de repouso foram semelhantes (78,28 vs. 63,51, p=0,40); pressões de contração (153,89 vs. 79,78, p=0,007) e pressão total de compressão (231,27 vs. 145,63, p=0,002). Os homens apresentaram valores significativamente maiores de contração esfincteriana, assim como o comprimento médio do canal anal funcional (2,85 cm nos homens vs. 2,45 cm nas mulheres, p=0,003). Conclusões: Os níveis normais de pressão esfincteriana no Brasil diferem dos utilizados até o momento como padrão normal da literatura. O gênero masculino apresenta maior tônus do esfíncter anal externo em relação ao feminino, além de maior extensão do canal anal funcional

ABSTRACT Background: Due to the lack of normal standards of anorectal manometry in Brazil, data used are subject to normality patterns described at different nationalities. Aim: To determine the values and range of the parameters evaluated at anorectal manometry in people, at productive age, without pelvic floor disorders comparing the parameters obtained between male and female. Methods: Prospective analysis of clinical data, such as gender, age, race, body mass index (BMI) and anorectal manometry, of volunteers from a Brazilian university reference in pelvic floor disorders. Results: Forty patients were included, with a mean age of 45.5 years in males and 37.2 females (p=0.43). According to male and female, respectively in mmHg, resting pressures were similar (78.28 vs. 63.51, p=0.40); squeeze pressures (153.89 vs. 79.78, p=0.007) and total squeeze pressures (231.27 vs. 145.63, p=0.002). Men presented significantly higher values of anorectal squeeze pressures, as well as the average length of the functional anal canal (2.85 cm in male vs. 2.45 cm in female, p=0.003). Conclusions: Normal sphincter pressure levels in Brazilians differ from those used until now as normal literature standards. Male gender has higher external anal sphincter tonus as compared to female, in addition a greater extension of the functional anal canal

This paper discusses 286 proposals and reports of Green Chemistry (GC) teaching experiences, in papers of the Journal of Chemical Education (JCEd) until 2019. The analysis was based on previous categories: source-problem, paper focus, subjects/area of knowledge, target groups, GC contents, type of approach and purpose(s) of the proposal. A list of possible characteristics of each category served as an example to compare with the information resulting from the analyses, and thus improve the discussions. In 127 papers, GC and its teaching were associated, albeit generally, with the theme of sustainability/sustainable development, which points to its potential to face environment-related aspects of chemistry in teaching. A systemic vision in the interconnection between GC and sustainability/sustainable development appeared more explicitly in 39 papers up to 2019. So far, the analysis highlights a certain reproduction of traditional chemistry teaching, and little evidence of the particularities of GC teaching. Despite the intention of inserting GC into chemistry teaching, proposals for its incorporation are often made superficially, more as an addendum or an extra quality than a specific goal. More methodological detail of the experiments carried out is needed to help in the dissemination of GC in the training curriculum of chemists. The discussions and reports on teaching approaches based on Systems Thinking showed the opening of a promising new methodological challenge within this theoretical paradigm.

The use of colorectal self-expanding metal stents (SEMS) as bridge therapy for malignant colorectal obstruction was first reported more than 20 years ago. However, its use remains controversial. Objective: In this study, we aimed to compare the long-term survival of patients with potentially resectable malignant colorectal obstruction who had undergone colorectal SEMS placement and emergency surgery. Methods: This study was a retrospective analyses. Patients who received treatment between 2009 and 2017 were included. According to the eligibility criteria, 21 patients were included in the SEMS group and 67 patients were included in the surgical group.. Results: The majority of the patients in the SEMS group were female (57.1%), whereas the majority of those in the surgical group were male (53.7%). The median follow-up time was 60 months for both groups with the same interquartile range of 60 months. There was no difference in the overall survival rate (log rank p=0.873) and disease-free survival rate (log rank p=0.2821) in the five-year analysis. There was no difference in local recurrence rates (38.1% vs. 22.4%, p=0.14) or distant recurrence rates (33.3% vs. 50.7%, p=0.16) in the SEMS and the surgical groups. Technical and clinical success rates of endoscopic stenting were 95.3% and 85.7%, respectively. There were no immediate adverse events (AEs). Severe AEs included perforation (14.3%), silent perforation (4.7%), reobstruction (14.3%), and bleeding (14.3%). Mild AEs included pain (42.8%), tenesmus (9.5%), and incontinence (4.76%). The limitations of this study was retrospective and was conducted at a single center. Conclusions: No differences in disease-free and overall survival rates were observed in the five-year analysis of patients with resectable colorectal cancer who had undergone SEMS placement or colostomy for the treatment of malignant colorectal obstruction. Patients in the SEMS group had a higher rate of primary anastomosis and a lower rate of temporary colostomy than did those in the surgery group.

Resumo A Química Verde é um movimento auto-organizado de químicos para prevenir e minimizar o uso e a produção de substâncias e processos perigosos. O atual número de publicações e a taxa de crescimento do campo dificultam a análise qualitativa de seu conteúdo, inovações (se houver) e dinâmica, portanto, novas metodologias devem ser estudadas. Esta pesquisa visa ampliar o entendimento sobre a estrutura da Química Verde apontando seus hubs intelectuais (pesquisadores importantes para a difusão e consolidação do conhecimento) e suas autoridades intelectuais, as fontes desse conhecimento. Documentos (N=14.142) contendo o termo “química verde” ou publicados no Green Chemistry Journal e no Green Chemistry Letters and Reviews entre 1990 e 2017 foram analisados por cocitação e análise de rede. Dezesseis clusters foram agrupados em seis grandes especialidades, das quais foram encontrados 14 hubs e 21 autoridades. Os resultados corroboram análises anteriores da área, mas esta pesquisa tem a vantagem de partir da dinâmica da produção científica, e não de categorias qualitativas da própria área previamente definidas.

Abstract Green Chemistry is a self-organized movement of chemists intended to prevent and minimize the use and production of dangerous substances and processes. The current output and growing rate of the field hinders descriptive analysis of its contents, innovations (if any), and dynamics. Therefore, new methodologies must be sought. This research aims at broadening the understanding on the structure of Green Chemistry by pointing out its intellectual hubs (researchers important to the spread and consolidation of knowledge) and its intellectual authorities, the sources of that knowledge. Documents (N=14,142) either containing the term “green chemistry” or published in the Green Chemistry Journal and the Green Chemistry Letters and Reviews between 1990 and 2017 were analyzed by co-citation and network analysis. Sixteen clusters were grouped in six big specialties, from which 14 hubs and 21 authorities were found. Results corroborate previous analyses of the field, but this research has the advantage of stemming from the dynamics of scientific production, rather than from previously defined qualitative categories of the field itself.

RESUMO Racional: A realização de procedimentos minimamente invasivos para o manejo de distúrbios colorretais, possibilitou ampliar a indicação de laparoscopia para o manuseio de diversas complicações pós-operatórias precoces e tardias. Objetivo: Apresentar a experiência com reoperações laparoscópicas para complicações precoces após ressecções colorretais laparoscópicas. Métodos: Foram incluídos pacientes submetidos a ressecções colorretais laparoscópicas que apresentaram complicações cirúrgicas no pós-operatório abordadas por via laparoscópica. Os pacientes selecionados foram aqueles com diagnóstico precoce de complicações, estabilidade hemodinâmica sem distensão abdominal significativa e sem comorbidades clínicas que impedissem o procedimento. Resultados: Em quatro anos, nove de 290 (3,1%) pacientes submetidos a ressecções colorretais laparoscópicas foram reabordados pela mesma via de acesso. Havia cinco pacientes do sexo masculino e idade média foi de 40,67 anos. Os diagnósticos de doença primária incluíram adenocarcinoma (n=3), polipose adenomatosa familiar (n=3), colite ulcerativa (n=1), inércia colônica (n=1) e megacólon chagásico (n=1). Os procedimentos iniciais incluíram quatro proctocolectomias totais com anastomose íleo-anal em bolsa ileal; três ressecções anteriores; uma totalização de colectomia total; e uma hemicolectomia direita. A deiscência da anastomose foi a complicação mais comum que resultou em reoperação (n=6). Houve apenas um caso de desfecho desfavorável, com óbito no 40º dia da primeira abordagem após complicações consecutivas. Os demais casos tiveram desfecho favorável . Conclusão: Em casos selecionados, o acesso laparoscópico pode representar alternativa de abordagem segura e minimamente invasiva para complicações da ressecção colorretal. No entanto, a reoperação laparoscópica deve ser cuidadosamente selecionada, considerando o tipo de complicação, a condição clínica do paciente e a experiência da equipe cirúrgica.

ABSTRACT Background: Recently, with the performance of minimally invasive procedures for the management of colorectal disorders, it was allowed to extend the indication of laparoscopy in handling various early and late postoperative complications. Aim: To present the experience with laparoscopic reoperations for early complications after laparoscopic colorectal resections. Methods: Patients undergoing laparoscopic colorectal resections with postoperative surgical complications were included and re-treated laparoscopically. Selection for laparoscopic approach were those cases with early diagnosis of complications, hemodynamic stability without significant abdominal distention and without clinical comorbidities that would preclude the procedure. Results: In four years, nine of 290 (3.1%) patients who underwent laparoscopic colorectal resections were re-approached laparoscopically. There were five men. The mean age was 40.67 years. Diagnoses of primary disease included adenocarcinoma (n=3), familial adenomatous polyposis (n=3), ulcerative colitis (n=1), colonic inertia (n=1) and chagasic megacolon (n=1). Initial procedures included four total proctocolectomy with ileal pouch anal anastomosis; three anterior resections; one completion of total colectomy; and one right hemicolectomy. Anastomotic dehiscence was the most common complication that resulted in reoperations (n=6). There was only one case of an unfavorable outcome, with death on the 40th day of the first approach, after consecutive complications. The remaining cases had favorable outcome. Conclusion: In selected cases, laparoscopic access may be a safe and minimally invasive approach for complications of colorectal resection. However, laparoscopic reoperation must be cautiously selected, considering the type of complication, patient’s clinical condition and experience of the surgical team.

RESUMO O presente trabalho traz resultados complementares de uma pesquisa anterior, que buscou responder: em que termos se observa a inserção do tema (in)sustentabilidade em trabalhos de teses e de dissertações que se caracterizaram como análise de práticas/ações de Educação em Ciências/Educação Científica e Tecnológica, com enfoque CTS, na abordagem de temas socioambientais. A abordagem sobre sustentabilidade carrega em si a valorização da dimensão ambiental, constituindo-se o core das discussões, especialmente no âmbito educacional, principalmente no contexto das relações CTS. Isso pressupõe ponderar sobre os impactos, por vezes irreversíveis, da exploração da natureza, principalmente sob a égide do capitalismo, o que inexoravelmente envolve o problema da insustentabilidade. Todavia, não se pode restringir a análise em apenas uma das dimensões dos processos insustentáveis, sob o risco de adotarmos uma concepção reducionista e fragmentada, apartada de uma abordagem multidimensional da questão. Em função da vigência de uma crise ambiental, o problema da insustentabilidade assume múltiplas dimensões, com inserção no campo social, econômico, ambiental, ético, entre outros, e sua abordagem tem referência forte nas relações CTS, mas apresenta-se subteorizada principalmente na sua vertente social. Assim, uma abordagem multidimensional das relações CTS na educação em ciências possibilita considerar a (in)sustentabilidade em sua multirreferencialidade de fatores. Ao revelar as convergências destes dois campos “Sustentabilidade e CTS”, no campo educacional, estaremos ampliando tanto a visão crítica das relações CTS quanto favorecendo a sensibilidade socioambiental.

ABSTRACT The present work shows complementary results of a previous research that aimed to answer: in what terms could be observed the insertion of the theme (in) sustainability in theses and dissertations that are characterized as analysis of practices/actions of Education in Sciences/Scientific and Technological Education, with STS focus and socio-environmental themes. The sustainability approach carries with it the appreciation of the environmental dimension, being the core of the discussions, especially in the context of STS relations. This presupposes pondering the irreversible impacts of exploitation of nature, especially under the aegis of capitalism, which inexorably involves the problem of unsustainability. However, the analyses can not be restricted to only one of the dimensions of unsustainable processes, with the risk of adopting a reductionist and fragmented approach, apart from a multidimensional approach to the issue. Therefore, due to the existence of an environmental crisis, the problem of unsustainability assumes multiple dimensions, with insertion in the social, economic, environmental and ethical fields, among others, and its approach has a strong reference in STS relations, but it is presented subtheoretically in its social aspect. Thus, a multidimensional approach to STS relationships in science education makes it possible to consider (in) sustainability in its multireferentiality of factors. In revealing the convergences of these two fields “Sustainability and STS”, in the educational field, we will be expanding both the critical view of STS relations and favoring socio-environmental sensitivity.

RESUMO O objetivo do estudo é avaliar os efeitos da fisioterapia na capacidade cognitiva e funcional de pacientes com doença de Alzheimer (DA). Trata-se de revisão sistemática de ensaios clínicos randomizados ou quasi-randomizados utilizando os descritores: DA, demência e fisioterapia. Dois estudos foram incluídos, com um total de 207 participantes. No Estudo 1, não houve diferença estatisticamente significativa no miniexame do estado mental (MEEM) (MD 0,0, IC 95% 5,76−5,76), inventário neuropsiquiátrico (MD −4,50, IC 95% 12,24−21,24) e questionário de atividades instrumentais Pfeffer (MD 0,0 IC 95% −6,48 a 6,48). No Estudo 2, não houve diferença estatisticamente significativa no MEEM (MD −1,60, IC 95% −3,57 a 0,37), teste do desenho do relógio (MD −0,20, IC95% −0,61 a 0,21) e escala de avaliação da doença de Alzheimer - subitem cognição (MD 1,0, IC95% −2,21 a 4,21) após 12 meses. Não houve evidência consistente da eficácia da intervenção fisioterapêutica na melhora da função cognitiva e capacidade funcional na DA. Recomenda-se a produção de mais estudos para encontrar possíveis evidências.

ABSTRACT The objective of this study is to evaluate the effects of physical therapy on the cognitive and functional capacity of patients with Alzheimer’s Disease (AD). This is a systematic review of randomized or quasi-randomized clinical trials, using the descriptors: AD, dementia and physical therapy. Two studies were included with a total of 207 participants. In study 1, no statistically significant difference was found on the mini-mental state examination (MMSE) (MD 0.0, 95%CI −5.76 to 5.76), neuropsychiatric inventory (MD −4.50, 95%CI −21.24 to 12.24) and Pfeffer instrumental activities questionnaire (MD 0.0 95%CI −6.48 to 6.48). In study 2, there was no statistically significant difference on the MMSE (MD −1.60, 95% CI −3.57 to 0.37), clock-drawing test (MD −0.20, 95%CI −0.61 to 0.21) and Alzheimer’s Disease Assessment Scale - cognitive subscale (MD 1.0, 95%CI −2.21 to 4.21) after 12 months. There was no consistent evidence on the effectiveness of physiotherapeutic intervention in improving cognitive function and functional capacity of patients with AD. More studies should be conducted for better evidence.

RESUMEN El presente estudio tiene como objetivo evaluar los efectos de la fisioterapia en la capacidad cognitiva y funcional de pacientes con enfermedad de Alzheimer (EA). Se trata de una revisión sistemática de ensayos clínicos aleatorizados o casi-aleatorizados, en que se utilizó los descriptores: EA, demencia y fisioterapia. Se incluyeron dos estudios, con un total de 207 participantes. En el Estudio 1, no hubo diferencias estadísticamente significativas en el Miniexamen del estado mental (MEEM) (MD 0,0, IC 95%: 5,6 -5,76), en el inventario neuropsiquiátrico (MD -4,50, IC 95%: 12,24 -21,24) y en el cuestionario de actividades instrumentales de Pfeffer (MD: 0,0 IC 95% IC: -6,48 a 6,48). En el Estudio 2, no hubo diferencias estadísticamente significativas en el MEEM (MD −1,60, IC 95% −3,57 a 0,37), el test de diseño del reloj (MD −0,20, IC 95% −0,61 a 0,21) y la escala de evaluación de la enfermedad de Alzheimer: subítem de cognición (MD 1,0, IC 95% −2,21 a 4,21) tras 12 meses. No hubo evidencia consistente de la eficacia de la intervención fisioterapéutica en la mejora de la función cognitiva y de la capacidad funcional en la EA. Se recomienda realizar estudios adicionales para encontrar posibles evidencias.

RESUMO. A Escala de Catherine Bergego (CBS) é uma escala para avaliar o impacto da negligência espacial unilateral (USN) no cotidiano de pacientes após AVC. Objetivo: Não há validação da CBS para população brasileira e o objetivo deste estudo foi avaliar a confiabilidade e compreensão da versão em português da CBS para pacientes com USN após AVC. Métodos: Trata-se de um estudo transversal em pacientes com AVC e USN. A CBS foi traduzida, adaptada culturalmente e aplicada por dois investigadores independentes. Os pacientes também foram avaliados pelo Behaviour Innatention Test (BIT), NIHSS, mRS e Barthel para avaliar a gravidade da USN, função neurológica, incapacidade e autonomia consecutivamente. A consistência e a coerência foram analisadas pelo coeficiente α de Cronbach, a confiabilidade interobservador foi avaliada pelo coeficiente kappa e a correlação entre o CBS, BIT, NIHSS, mRS e Barthel foi avaliada pela correlação de Pearson. Resultados: Vinte e dois pacientes foram avaliados e observaram-se consistência e coerência pelo coeficiente α de Cronbach=0,913. Na análise da reprodutibilidade intraobservador, os 10 itens da escala apresentaram confiabilidade razoável e alta entre os avaliadores. O CBS mostrou correlação negativa com o BIT. Houve baixa correlação entre BIT e NIHSS, mRS e índice de Barthel. Conclusão: A CBS é uma escala adequada e validada para avaliar pacientes com USN após AVC em uma população brasileira e de língua portuguesa.

ABSTRACT. The Catherine Bergego Scale (CBS) is a scale to evaluates the impact of unilateral spatial neglect (USN) on everyday life of patients after stroke. Objective: The aim of this study was to evaluate the reliability and comprehension of the Portuguese version of the CBS for patients with USN after stroke. Methods: This was a cross-sectional study in patients with stroke and USN. The CBS was translated, culturally adapted and applied by two independent investigators. The patients were also evaluated by the Behavioural Inattention Test (BIT), NIHSS, mRS and Barthel scale to assess USN severity, neurological function, disability and autonomy consecutively. Consistency and coherence were analysed using Cronbach’s α, inter-observer reliability by Kappa, and the correlation between the CBS, BIT, NIHSS, mRS, and Barthel was determined using Pearson correlation. Results: Twenty-two patients were evaluated and the observed Cronbach’s α=0.913. For intra-observer reproducibility, the 10 items showed a reasonable and high reliability between evaluators. The CBS showed a negative correlation with the BIT. There was a low correlation between the BIT and NIHSS, mRS and Barthel index. Conclusion: The CBS is an adequate and validated scale for assessing patients with USN after stroke in a Brazilian population.

RESUMO Racional: Desde 1990, foi proposto que a localização distal e proximal do câncer de cólon pode seguir diferentes aspectos biológicos, epidemiológicos, patológicos e prognósticos. Essas diferenças podem ter consequências para o tratamento de pacientes com câncer colorretal. Objetivo: Comparar as características entre pacientes com câncer de cólon direito e esquerdo, com gravidade e características tumorais que influenciam na sobrevida desses pacientes. Método: Avaliação dos resultados do tratamento cirúrgico dos pacientes com câncer de cólon em longo prazo com dados coletados retrospectivamente. Resultados: O lado do tumor não influenciou o tempo de sobrevida (p=0,112) no modelo de regressão. Apenas o estágio da doença influencia no tempo de sobrevida. Os pacientes com câncer de cólon direito apresentam estadiamento mais avançado (III ou IV) e apresentam risco de morte 3,23 vezes maior. Conclusão: O prognóstico do câncer de cólon localizado no lado esquerdo é melhor comparado ao direito. Os pacientes com câncer de cólon direito têm estágio e idade mais avançados e tumor mucinoso.

ABSTRACT Background: Since 1990 it was proposed that distal and proximal location of colon cancer might follow different biological, epidemiology, pathology and prognosis, probably due to embryologic different development of the two segments of the colon, which may represent two separate disease entities. These differences might have consequences for the treatment of patients with colorectal cancer. Aim: To compare the characteristics between patients with right and left colon cancer, with severity and tumor characteristic that influence in the survival of these patients. Method: Were evaluated the outcomes of surgical treatment of patients with colon cancer with data collected retrospectively from prospectively collected database. Results: The tumor’s side did not influence survival time of patients with colon cancer (p=0.112) in the regression model. Only the diseases stage leads to influence on survival time; patients with right colon cancer have more advanced staging (III or IV) and present a risk of death greater in 3.23 times. Conclusion: This analysis provides evidence that the prognosis of localized left-sided colon cancer is better compared to right-sided colon cancer. Also, the patients with right colon cancer have more advanced stage, mucinous tumor and are older.

Ectopic pregnancy, a potentially life-threatening condition, represents 1-2% of all pregnancies. Tubal pregnancy represents about 95% of the cases, but other locations can occur such as ovary, uterine cervix and abdominal cavity. Abdominal pregnancy is a rare event, seen in about 1.3% of ectopic pregnancies. We present a case of abdominal pregnancy located at the Douglas pouch and superficially infiltrated the rectovaginal septum in a woman under intra-uterine device contraception.